Dr. Shiple is a recognized leader of Ultrasound-guided Orthobiologics, including Bone Marrow Concentrate, Adipose Fat Grafts, PRP, and prolotherapy injection work in the Philadelphia area and nationally. He has been in private practice for more than 12 years and spent 13 years as the division chief of Sports Medicine for Crozer-Keystone Health System, where he also directed and founded the Sports Medicine Fellowship program in 1995. He has been using autologous stem cell injections to treat advanced arthritis and sports injuries since 2010 and is a founding board member of the International Cellular Medicine Society. He believes the future of the specialty is to use advanced regenerative orthobiologic cell-based treatments with minimally invasive techniques in a new specialty called Interventional Regenerative Orthopedic Medicine (IROM).